Natural Skin Regeneration by Mr Juling Ong, Consultant Plastic Surgeon

Among the most innovative non-surgical treatments now available are polynucleotide injections — a science-driven method to restore skin vitality from within.

For patients seeking a fresher, more youthful appearance without adding artificial volume or limiting natural facial movement, polynucleotides offer an elegant, biologically active alternative.

They work by stimulating the skin’s own repair and regeneration mechanisms, improving texture, hydration, and elasticity for smoother, more radiant skin.

What are Polynucleotides?

Polynucleotides are long chains of nucleotides — the natural building blocks of DNA. When introduced into the skin, they act as biostimulators, triggering the body’s wound-healing and tissue-repair processes.

This leads to increased collagen and elastin production, improved cell turnover, and enhanced moisture retention — key factors in restoring skin quality and resilience.

The polynucleotides used in aesthetic medicine are purified from salmon or trout DNA, a source highly compatible with human tissues. Once injected beneath the skin’s surface, they promote deep biological renewal rather than superficial filling, resulting in a gradual, natural improvement in tone, firmness, and radiance.

Benefits of Polynucleotide Treatment

• Improves fine lines and wrinkles
• Reduces under-eye circles and puffiness
• Enhances hydration and elasticity
• Refines skin texture and tone
• Reduces pigmentation and sun damage
• Suitable for the face, neck, and décolletage

Polynucleotides are particularly suited to patients who wish to age gracefully — maintaining their natural expressions while restoring a more refreshed, youthful appearance.